Rudy Giuliani is pulling out the big guns to hype hydroxychloroquine — his alleged mistress, to be precise.

Beltway insiders were amused to hear the former NYC mayor interview Maria Ryan — the woman with whom Giuliani denied having an affair after ex-wife Judy claimed they were still married when Ryan and Giuliani got together — as a medical expert on his radio show, “Uncovering the Truth.”

The insiders also noted with some glee that he framed her as a medical expert and kept calling her “doctor” — even though her doctorate is in hospital administration and came from an online university that shut down after a failed attempt to become accredited, according to reports.

The pair didn’t mention their off-air relationship during the Memorial Day chat, in which they claimed that hydroxychloroquine is broadly safe and effective to fight COVID-19.

“It’s pretty sad to see Rudy’s decline from ‘America’s mayor’ to hawking snake oil cures on a radio show that no one listens to,” said a DC insider. “At this rate, he’s going to be touting drinking bleach as a coronavirus cure on late-night infomercials before too long.”